Bottom line up front
Prehospital whole blood facts
- Hemorrhage is the leading cause of preventable death in trauma, and early blood transfusion can save lives
- Between 260,000 and 1.2 million trauma patients annually could benefit from prehospital blood transfusions
- Despite the high demand, less than 1% of eligible trauma patients received prehospital blood transfusions between 2020 and 2023
Prehospital whole blood takeaways
- The need for prehospital blood transfusions is growing, but utilization remains alarmingly low
- EMS agencies face significant barriers, including cost, lack of standardized protocols and reimbursement issues
- The underuse of blood products in the field highlights a critical gap in trauma care that directly impacts patient survival
Prehospital whole blood next steps
- Standardize national protocols for prehospital blood transfusion to ensure consistent application across EMS agencies
- Increase funding and reimbursement to make blood products more accessible for EMS agencies
- Improve blood product access, especially in underserved areas, and enhance data collection to track usage and demand
You don’t need me to tell you that hemorrhage, or severe bleeding, is the leading cause of preventable death in trauma patients. As EMS professionals, we all know how critical it is to stop the bleeding before it’s too late. Yet, despite a growing body of evidence that prehospital blood transfusions could save lives, less than 1% of eligible trauma patients actually receive this vital intervention. The latest study, “Nationwide Trends in Prehospital Blood Product Use After Injury,” confirms that the demand for prehospital blood transfusions is growing, but implementation is lagging.
|More: Barriers to prehospital whole blood implementation
The stark reality: A life-saving intervention left untapped
Published in “Transfusion” in April 2025, the study used data from the National Emergency Medical Services Information System (NEMSIS) from 2020 to 2023 to measure the potential demand for prehospital blood transfusion. What they found is both eye-opening and frustrating: between 260,000 and 1.2 million trauma patients annually could benefit from blood products in the field, yet only a fraction — less than 1% — actually receive them.
Trauma-induced hemorrhagic shock is a deadly condition, but early intervention with blood products can drastically improve outcomes. If you’re in the field, you know that trauma is all about timing. The faster we can stabilize patients with life-saving interventions, the better their chances of survival. But for too many patients, prehospital blood transfusions are still a rarity.
The roadblocks: Why are blood transfusions so rare in the field?
The answer is a combination of logistical, financial and policy-related barriers. While several EMS agencies, particularly in regions like Texas and North Carolina, have pioneered programs to carry blood products in the field, these efforts remain the exception rather than the rule. By 2024, only about 1% of EMS agencies nationwide were equipped to administer prehospital blood transfusions. For the vast majority of EMS providers, this resource simply isn’t available.
1. Cost and supply limitations
Blood products are expensive. The cost of providing a prehospital blood transfusion can run upwards of $1,000 per patient. Given that many EMS agencies, particularly in rural or volunteer settings, operate under tight budgets, it’s no surprise that the expense of blood products is a significant barrier to their use. Adding to this challenge is the fact that blood banks and hospitals are often the sole suppliers of blood for EMS agencies, placing additional strain on already stretched resources.
2. No standardized protocols
There’s no national standard for when EMS should administer blood transfusions. Although groups such as the Prehospital Blood Transfusion Coalition are spearheading efforts to develop such a standard, it’s currently up to each individual agency and provider to decide. This lack of consistency means that some agencies use blood products, while many others don’t — even though they could save lives with them. We need uniform guidelines to ensure blood products are used consistently across all EMS agencies, regardless of where they operate.
3. Reimbursement issues
Many EMS agencies aren’t reimbursed for prehospital blood transfusions, leaving them to foot the bill. This lack of financial incentive makes it even harder for agencies to justify carrying blood products. Moreover, EMS documentation practices are often not robust enough to capture blood product usage consistently, meaning some patients who receive transfusions in the field may not have their treatment properly recorded.
A growing need: The demand for prehospital blood is increasing
One thing the study makes abundantly clear is that the need for prehospital blood transfusions is only rising. In 2020, about 54,000 trauma patients met the criteria for needing blood, and by 2023, that number had jumped to 75,000 — a clear sign that this demand is growing. Meanwhile, the actual use of prehospital blood transfusions remained low, with only 0.64% of patients in 2020 and 0.88% in 2023 receiving them. That’s a frustratingly small increase considering the increasing number of patients who could benefit from this intervention.
As EMS professionals, we know that when someone’s bleeding out, every minute counts. So why aren’t we doing more to meet this growing demand?
Overcoming the barriers: A path forward for EMS
If we’re serious about saving more lives, we need to break down the barriers standing in the way of prehospital blood transfusion. Here’s how we can do it:
- Standardize national protocols. We need a unified approach to prehospital blood transfusions. While every EMS agency should have the flexibility to make decisions based on their local context, we must develop national guidelines to help every provider make the right call. Blood products should be used when patients show clear signs of hemorrhagic shock — this isn’t a grey area.
- Increase funding and reimbursement. This isn’t just a financial burden on EMS agencies — it’s a national issue. Congress and state governments need to step up and provide financial support to EMS agencies that are willing to carry blood products. Until there’s a clear pathway for reimbursement, the financial burden will remain a significant roadblock.
- Expand blood product access. EMS agencies need easier access to blood products, especially in high-need areas. Partnering with regional blood banks and hospitals to ensure a steady and reliable supply of blood could be the key to making blood products available to more EMS agencies. This includes hosting and facilitating blood drives. Blood products shouldn’t be something that only certain regions have access to — they should be available wherever trauma patients need them.
- Improve documentation and data reporting. Better documentation practices will ensure that the use of blood products is tracked more accurately. This data will help further refine protocols and demonstrate the impact of prehospital blood transfusions on patient outcomes.
The bottom line: We can’t afford to wait
The findings of this study are sobering, but they also provide us with a clear call to action. The potential to save lives with prehospital blood transfusions is high — but so is the unmet need. Trauma patients are dying because the systems we have in place aren’t designed to meet the demand for blood products in the field. The evidence is there, the need is clear, and the time to act is now.
EMS professionals are at the tip of the spear in trauma care. We are the first responders on the scene, and it’s time we had the tools to match the urgency of the situations we face. With strategic investments in infrastructure, training and policy changes, we can save more lives and reduce preventable deaths from traumatic hemorrhage.
This isn’t just about carrying blood products — it’s about delivering on our promise to save lives, no matter where or when the call comes in. Let’s make sure that when it matters most, we have the blood on hand to make a difference.
Additional whole blood resources:
- Carico C, Annesi C, Clay Mann N, Levy MJ, et al. “Nationwide trends in prehospital blood product use after injury,” 2025. Transfusion – Wiley Online Library
- Tracking the whole blood landscape as updated guidelines allow EMS to carry and administer whole blood
- EMS One-Stop: Stop the bleed, fill the tank – The New Orleans EMS blood program
- Insider analysis: Delaware’s statewide whole blood rollout sets a new EMS standard
- Whole blood in EMS promises a revolution in resuscitation: How one county agency is saving lives with prehospital transfusions
- Matthew Levy | LinkedIn
- Christine Carico | LinkedIn