TXA for GI bleeds?

What the HALT-IT study reveals about the potential dangers of TXA for acute hemorrhage


We’ve discussed TXA in trauma and TXA in epistaxis. Medics often ask about TXA in acute gastrointestinal bleed patients who are in hemorrhagic shock. “What can it hurt? It’s worth a try, right?”

The HALT-IT, a prospective, randomized, multi-center, international study, looked at mortality and rebleeding in over 12,000 GI bleeds (upper and lower) from 2013-2019.

While TXA may seem like a harmless hail Mary, on this episode of the MCHD Paramedic Podcast, MCHD Medical Director Dr. Casey Patrick reviews the HALT-IT study and discusses why TXA for acute GI bleeds may be harmful.


Listen to next: From TXA to REBOA: Advances in trauma care

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